Method Development and Validation of Metronidazole Using UV Spectrophotometer

Metronidazole in METRONIDAZOLE I.V. Infusion 500mg/100ml was determined by Spectrophotometric method. Being a very simple, reliable and sensitive method was developed and adopted to perform the analysis of METRONIDAZOLE I.V. Infusion 500mg/100ml. The Spectrophotometric method described was found to be simple, sensitive and accurate. Therefore this could be applied for the determination of METRONIDAZOLE I.V. Infusion 500mg/100ml.The results obtained confirm the suitability of the proposed method for the precise analysis of the drug. Based on the above results, the test method is found to be specific, linear, precise, reproducible and accurate. So, it has been concluded that test method for METRONIDAZOLE I.V. Infusion 500mg/100mlcan be used for routine testing in Quality Control Laboratory. Since the suggested method is simple and reliable, this can be used for routine analysis of METRONIDAZOLE I.V. Infusion 500mg/100mlInjection in the Quality Control Laboratory to release the commercial batches.